Influence of blood-promoting and water-disinhibiting therapy on neurological function of massive cerebral infarction patients following decompressive hemicraniectomy

WANG Jing-yu; KONG Ling-jun; XU Le-yi; FEI Zhi-min

您当前的位置：

首页 >

文章列表页 >

Influence of blood-promoting and water-disinhibiting therapy on neurological function of massive cerebral infarction patients following decompressive hemicraniectomy

更新时间：2022-08-31

- Influence of blood-promoting and water-disinhibiting therapy on neurological function of massive cerebral infarction patients following decompressive hemicraniectomy
- Shanghai Journal of Traditional Chinese Medicine Vol. 50, Issue 12, Pages: 50-52(2016)
- 作者机构：
  
  1. 上海中医药大学附属曙光医院神经外科,上海,200021
- 作者简介：
- 基金信息：
- DOI：
  CLC：
扫描看全文
WANG Jing-yu, KONG Ling-jun, XU Le-yi, et al. Influence of blood-promoting and water-disinhibiting therapy on neurological function of massive cerebral infarction patients following decompressive hemicraniectomy. [J]. Shanghai Journal of Traditional Chinese Medicine 50(12):50-52(2016)
DOI：

WANG Jing-yu, KONG Ling-jun, XU Le-yi, et al. Influence of blood-promoting and water-disinhibiting therapy on neurological function of massive cerebral infarction patients following decompressive hemicraniectomy. [J]. Shanghai Journal of Traditional Chinese Medicine 50(12):50-52(2016) DOI：

摘要

目的：观察活血利水法对大面积脑梗死去骨瓣减压术后患者神经功能的影响。方法：将60例脑梗死术后患者随机分为对照组和治疗组(各30例),均给予常规西药治疗,治疗组加服活血利水方药治疗,疗程14天。观察两组治疗前后神经功能缺损程度(NIHSS)评分,血清超氧化物歧化酶(SOD)和脂质过氧化物(LPO)含量变化。结果：治疗后,两组NIHSS评分均较治疗前降低(P<0.05,P<0.01),且治疗组低于对照组(P<0.01)。治疗后,两组LPO含量均较治疗前降低(P<0.01),且治疗组低于对照组(P<0.01)；两组SOD含量均较治疗前升高(P<0.01),且治疗组高于对照组(P<0.01)。结论：活血利水法可通过抗氧化和清除氧自由基作用改善脑梗死术后患者神经功能。

Abstract

Objective:To observe the effects of blood-promoting and water-disinhibiting therapy on neurological function of massive cerebral infarction patients following decompressive hemicraniectomy. MethodsSixty subjects were randomly divided into the treatment group and control group (30 cases in each group), and treated with routine therapies of western medicine. The treatment group was additionally given the prescription herbs of blood-promoting and water-disinhibiting, with a course of 14 days. The NIH stroke scales (NIHSS), and the serum levels of superoxide dismutase (SOD) and lipid peroxides (LPO) were observed before and after treatment. Results:After treatment, the NIHSS was decreased in both groups compared with the treatment before(P<0.05,P<0.01), and that in the treatment group was lower than that in the control group(P<0.01). The level of LPO was decreased in both groups compared with the treatment before (P<0.01), and that in the treatment group was lower than that in the control group (P<0.01). The level of SOD were increased in both groups compared with the treatment before (P<0.01), and that in the treatment group was higher than that in the control group (P<0.01). Conclusion: The blood-promoting and water-disinhibiting therapy may improve neurological function of postoperative patients with cerebral infarction through anti-oxidation and scavenging oxygen free radicals.

关键词

脑梗死活血利水法神经功能缺损超氧化物歧化酶(SOD)脂质过氧化物(LPO)

Keywords

cerebral infarctionblood-promoting and water-disinhibiting therapyneurological deficitsuperoxide dismutase(SOD)lipid peroxides(LPO)

references

Views

下载量

CSCD

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Clinical study on effect of Shengyang Tongdu acupuncture on electroencephalography topography, neurovascular unit function and heart rate variability in patients with cerebral infarction

Clinical efficacy observation of massage and acupoint pressure in the treatment of spastic hemiplegia of upper limb after cerebral infarction

Clinical study of the influence of Yijinjing on motor function and life quality of convalescent patients with cerebral infarction

Combination of acupuncture and moxibustion therapy and therapeutic apparatus for the cerebral hemiplegia rehabilitation

Related Author

No data

Related Institution

Department of Rehabilitation Medicine, the First Affiliated Hospital of Hebei North University

School of Further Education,Shanghai University of Traditional Chinese Medicine

Department of Rehabilitation,Third People’s Hospital of Chongming District

School of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine

Department of Rehabilitation,Yueyang Hospital of Integrated Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine

⁰