Effects of “Shenling Baizhu Powder” on serum gastrointestinal hormones and electrogastrogram in children with functional dyspepsia of spleen deficiency and qi stagnation

LUO Jun; XU Chun-yan; ZHAO Kai

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Effects of “Shenling Baizhu Powder” on serum gastrointestinal hormones and electrogastrogram in children with functional dyspepsia of spleen deficiency and qi stagnation

更新时间：2022-08-31

- Effects of “Shenling Baizhu Powder” on serum gastrointestinal hormones and electrogastrogram in children with functional dyspepsia of spleen deficiency and qi stagnation
- Shanghai Journal of Traditional Chinese Medicine Vol. 50, Issue 10, Pages: 50-52(2016)
- 作者机构：
  
  1. 浙江省义乌市北苑街道社区卫生服务中心,浙江义乌,322000
  2. 浙江省义乌市中医医院中医儿科,浙江义乌,322000
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LUO Jun, XU Chun-yan, ZHAO Kai. Effects of “Shenling Baizhu Powder” on serum gastrointestinal hormones and electrogastrogram in children with functional dyspepsia of spleen deficiency and qi stagnation. [J]. Shanghai Journal of Traditional Chinese Medicine 50(10):50-52(2016)
DOI：

LUO Jun, XU Chun-yan, ZHAO Kai. Effects of “Shenling Baizhu Powder” on serum gastrointestinal hormones and electrogastrogram in children with functional dyspepsia of spleen deficiency and qi stagnation. [J]. Shanghai Journal of Traditional Chinese Medicine 50(10):50-52(2016) DOI：

摘要

目的：观察参苓白术散对脾虚气滞型功能性消化不良(FD)患儿血清胃肠激素及胃电图的影响。方法：将120例脾虚气滞型FD儿童随机分为观察组和对照组,各60例；对照组给予莫沙必利治疗,观察组在对照组基础上给予参苓白术散,疗程2周。观察两组治疗前后血清胃动素(MTL)、神经肽(NPY)、5-羟色胺(5-HT)及胃电图变化。结果：①治疗后,两组NPY、MTL水平均较治疗前明显上升(P<0.05),5-HT水平则明显下降(P<0.05)；且观察组的变化大于对照组(P<0.05)。②治疗后,两组胃体和胃窦胃电图指标均有一定改善(P<0.05),且观察组改善优于对照组(P<0.05)。结论：参苓白术散治疗脾虚气滞型FD的作用机制是改善患儿胃肠动力。

Abstract

Objective:To observe the effects of “Shenling Baizhu Powder” on serum gastrointestinal hormones and electrogastrogram in children with functional dyspepsia of spleen deficiency and qi stagnation. MethodsOne hundred and twenty subjects were divided into the observation group and control group, 60 cases in each group. The control group was given Mosapride, and the observation group was given “Shenling Baizhu Powder” and Mosapride, with a course of two weeks. The changes of serum motilin(MTL), neuropeptide Y(NPY)5-serotonin(5-HT) and electrogastrogram were observed before and after treatment in both groups. Results:①After treatment, in both groups, the levels of NPY and MTL increased(P<0.05) and 5-HT decreased (P<0.05), with more significant improvement in the observation group than in the control group(P<0.05). ②After treatment, the electrogastrogram in gastric corpus and antrum were all improved in both groups(P<0.05), with more significant improvement in the observation group than in the control group(P<0.05). Conclusion:“Shenling Baizhu Powder” acts to treat functional dyspepsia of spleen deficiency and qi stagnation by improving gastrointestinal motility.

关键词

功能性消化不良脾虚气滞型参苓白术散儿童

Keywords

functional dyspepsiaspleen deficiency and qi stagnation“Shenling Baizhu Powder”children

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