In this paper data mining technology was used in study of using drugs regularity of Professor Zhu Huirong in treating colorectal cancer. Professor Zhu pays more attention to heat clearing and detoxifying, Kidney Tonifying and Phlegm Resolving, yin nourishing to moisten dryness in drug using. In clinical application, Professor Zhu usually uses the combination of cold medicine and warming medicine, and she is good at using drug pairs.