The sentence of “Observe symptoms to know how it committed against, and then follow the legislation to treat syndromes” shows the idea and process of diagnosis of Treatise On Febrile Diseases, and it is the collection of pulse and symptoms, embodies the dialectical thinking and methods of “pulse–certificate”. It is also the prototype of syndrome differentiation and treatment, laying a solid foundation for the establishment of TCM syndrome differentiation and treatment. At the same time, it also shows that “recognize pulse and symptoms”, “identify pulse and symptoms” occupies an important position in the clinical syndrome differentiation of TCM.