Mechanism of “Laifu Chengqi Decoction” in promoting gastrointestinal function in rats after subtotal gastrectomy
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Mechanism of “Laifu Chengqi Decoction” in promoting gastrointestinal function in rats after subtotal gastrectomy
Shanghai Journal of Traditional Chinese MedicineVol. 49, Issue 6, Pages: 85-86(2015)
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1. 河北省唐山市第三医院ICU科,河北,唐山,063100
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ZHANG Hai-bo, ZHAO Jin-liang. Mechanism of “Laifu Chengqi Decoction” in promoting gastrointestinal function in rats after subtotal gastrectomy. [J]. Shanghai Journal of Traditional Chinese Medicine 49(6):85-86(2015)
DOI:
ZHANG Hai-bo, ZHAO Jin-liang. Mechanism of “Laifu Chengqi Decoction” in promoting gastrointestinal function in rats after subtotal gastrectomy. [J]. Shanghai Journal of Traditional Chinese Medicine 49(6):85-86(2015)DOI:
Mechanism of “Laifu Chengqi Decoction” in promoting gastrointestinal function in rats after subtotal gastrectomy
Objective:To investigate the influence of “Laifu Chengqi Decoction” on gastrointestinal function in rats after subtotal gastrectomy Methods:Thirty SD rats were randomized into model group, treatment group and sham group, ten rats in each group. Twenty-four hours after subtotal gastrectomy, treatment group was treated with “Laifu Chengqi Decoction”(5 g/kg), sham group and model group with the same volume of saline(10 ml/kg), with a course of 21 days. The amount of food intake, body weight, and the levels of urine D-xylose and serum leptin were observed Results:①Compared with the model group, the amount of food intake and body weight were increased in the treatment group and sham group(P<0.05). ②Compared with the model group, the levels of urine D-xylose were increased and the levels of serum leptin were reduced in the treatment group and sham group(P<0.05) Conclusion:“Laifu Chengqi Decoction” can promote the restoration of gastrointestinal function after subtotal gastrectomy by increasing gastrointestinal absorption and decreasing serum leptin.