Clinical research of combining therapy of Chinese medicine on T-lymphocyte and immune globulin in patients with acute mastitis

CHEN Hao; XIA Ya-ru; CHENG Yi-qin; CHEN Li-ying; YE Mei-na; CHEN Hong-feng

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Clinical research of combining therapy of Chinese medicine on T-lymphocyte and immune globulin in patients with acute mastitis

更新时间：2022-08-31

- Clinical research of combining therapy of Chinese medicine on T-lymphocyte and immune globulin in patients with acute mastitis
- Shanghai Journal of Traditional Chinese Medicine Vol. 49, Issue 5, Pages: 63-65(2015)
- 作者机构：
  
  1. 上海中医药大学附属龙华医院乳腺科,上海,200032
- 作者简介：
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CHEN Hao, XIA Ya-ru, CHENG Yi-qin, et al. Clinical research of combining therapy of Chinese medicine on T-lymphocyte and immune globulin in patients with acute mastitis. [J]. Shanghai Journal of Traditional Chinese Medicine 49(5):63-65(2015)
DOI：

CHEN Hao, XIA Ya-ru, CHENG Yi-qin, et al. Clinical research of combining therapy of Chinese medicine on T-lymphocyte and immune globulin in patients with acute mastitis. [J]. Shanghai Journal of Traditional Chinese Medicine 49(5):63-65(2015) DOI：

摘要

目的：探讨粉刺性乳痈患者T淋巴细胞、免疫球蛋白水平的变化情况,观察中医综合疗法的临床疗效及其对相关免疫指标的影响方法：①以30例健康女性志愿者为正常组,观察60例患者(治疗组)T淋巴细胞、免疫球蛋白水平的变化情况。②治疗组患者采用中医综合疗法(手术、疏肝清热中药内服、中药外治)进行治疗,疗程为2个月；观察临床疗效及其对T淋巴细胞、免疫球蛋白水平的影响结果： ①治疗后,治疗组患者全部治愈,总有效率达100%。②治疗组治疗前与正常组比较,CD4,+,、CD8,+,水平降低；组间比较,差异有统计学意义(P,<,0.05)。治疗组治疗后与本组治疗前比较,CD3,+,、CD4,+,、CD4,+,/CD8,+,水平升高,差异有统计学意义(P,<,0.05)。③治疗组治疗前与正常组比较,IgG水平升高；组间比较,差异有统计学意义(P,<,0.05)。治疗组治疗后与本组治疗前比较,IgG、IgA水平降低,差异有统计学意义(P,<,0.05) 结论：粉刺性乳痈与免疫平衡紊乱有关,中医综合疗法对粉刺性乳痈外周血T淋巴细胞和免疫球蛋白具有调节作用。

Abstract

Objective:To observe the of combining therapy of Chinese medicine on T-lymphocyte and immune globulin in patients with acute mastitis Methods:①Thirty female patients as the normal group, and we observed the changes of T-lymphocyte and immune globulin in 60 cases. ②Patients in the treatment group was treated with combining therapy of Chinese medicine for 2 months. The clinical efficacy, and T-lymphocyte and immune globulin were observed Results:①After treatment, all patients in the treatment group were observed, and the total effective rate was 100%. ②Before treatment, there were significant differences in the levels of CD4,+, and CD8,+, between the two groups (P,<,0.05); in the treatment group, there were significant differences in the levels of CD3,+, CD4,+, and CD4,+,/CD8,+, between before and after treatment (P,<,0.05). ③There were significant differences in the IgG level between the two groups (P,<,0.05). There were significant differences in the IgG and IgA levels between before and after treatment (P,<,0.05) Conclusion:Acute mastitis has close relationship with disorder of immunologic balance, and combining therapy of Chinese medicine has regulatory effect on T-lymphocyte and immune globulin in patients with acute mastitis.

关键词

粉刺性乳痈浆细胞性乳腺炎疏肝清热法T淋巴细胞免疫球蛋白

Keywords

acute mastitisplasma cell mastitissoothing liver and clearing heat methodT-lymphocyteimmune globulin

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