Objective:To observe the clinical efficacy of “Elian Granules” in treating chronic atrophic gastritis (CAG) of spleen deficiency and heat stagnation pattern accompanied with intestinal metaplasia  Methods:Ninety cases with CAG of spleen deficiency and heat stagnation pattern accompanied with intestinal metaplasia were randomized into three groups:treatment A group (group A), treatment B group (group B) and control group (group C), with 30 cases in each group. Group C was treated with “Wei Fuchun Tablets”, group B was treated with “Elian Granules” at the common dosage and group A was treated with “Elian Granules” at the high dosage, with the course of 12 weeks. The safety was evaluated  Results:① Eighty cases finished the trail, with 28 cases in group A, 26 cases in group B and 26 cases in group C. ② For full analysis set (FAS), the clinical efficacy was 96.67%, 93.33% and 66.67% respectively, with significant difference among these groups (P<0.05), and there were also significant difference between group A and C as well as between group B and C (P<0.05). ③ In each group, there was significant differences in grade of atrophy and intestinal metaplasia between before and after treatment (P<0.05); after treatment, significant difference was found in grade of atrophy and intestinal metaplasia between group A and C as well as group B and C (P<0.05). ④ In each group, there was significant difference in TCM symptoms after treatment (P<0.05). ⑤ No significant difference was found in occurrence rate of adverse reaction among the groups (P>0.05)  Conclusion:“Elian Granules” can effectively improve the clinical symptoms and safely reverse the gastric mucosa pathology in patients with CAG accompanied with intestinal metaplasia.